Melanotan 2 (MT-II) is an analog of alpha-melanocyte stimulating hormone (a-MSH). This protein peptide hormone has an effect on body composition, feeding, fatty acid oxidation and metabolism to name a few. MT-II use is common among fitness enthusiasts and now possibly the obese as a melanocortin diet aid.
The central melanocortin system is important in the control of food intake and body weight. Melanotan 2 suppress food after administration. Disruptions in melanocortin receptors (MCR) have been found to be the cause of obesity in some.
Melanocortins have a direct effect on adipocytes through lipid mobilization. Increasing evidence is showing peripheral action of leptin expression in the adipocytes. Future valuable insight in regards to melanocortin peptides could be used to improve insulin sensitivity by stimulating fatty acid oxidation.
Energy balance and food intake are critical pathways that the melanocortin system regulate. The melanocortin system is critical signaling pathway for the actions of adiposity signals such as leptin and insulin. Data shows reduced food intake being primarily responsible for weight loss on Melanotan 2, among other (energy, etc) mechanisms. MT-II reduces food intake until lowered leptin levels are attained. Dosing while fasting could prove to reduce both visceral and subcutaneous adipose compartments.
Robust reductions in food consumption and body weight occur from Melanotan 2. The body adjusts to the energy and food intake through continuous applications. If taken intermittently a user can sustain a appetite reduction after administration. Regardless, both continuous and intermittent MT-II regimens produce body fat and weight reduction. The fourth MCR is conceivably the channel that can stimulate fat oxidation.
Melanotan 2 applications result in remarkable and sustainable weight and fat loss. Learn more at Melanotan Headquarters today!